Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8ayx
Q-score: 0.649
Bahar MW, Nasta V, Fox H, Sherry L, Grehan K, Porta C, Macadam AJ, Stonehouse NJ, Rowlands DJ, Fry EE, Stuart DI
Commun Biol (2022) 5 pp. 1293-1293 [ DOI: doi:10.1038/s42003-022-04252-5 Pubmed: 36434067 ]
- Capsid protein, vp3 (26 kDa, Protein from Human poliovirus 3)
- Human poliovirus 3 (5 MDa, Virus from Human poliovirus 3)
- Capsid protein, vp1 (33 kDa, Protein from Human poliovirus 3)
- 1-[(3s)-5-[4-[(e)-ethoxyiminomethyl]phenoxy]-3-methyl-pentyl]-3-pyridin-4-yl-imidazolidin-2-one (410 Da, Ligand)
- Capsid protein, vp0 (37 kDa, Protein from Human poliovirus 3)
- Glutathione (307 Da, Ligand)
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 8ayy
Q-score: 0.647
Bahar MW, Nasta V, Fox H, Sherry L, Grehan K, Porta C, Macadam AJ, Stonehouse NJ, Rowlands DJ, Fry EE, Stuart DI
Commun Biol (2022) 5 pp. 1293-1293 [ DOI: doi:10.1038/s42003-022-04252-5 Pubmed: 36434067 ]
- Capsid protein, vp3 (26 kDa, Protein from Human poliovirus 3)
- Human poliovirus 3 (5 MDa, Virus from Human poliovirus 3)
- Capsid protein, vp1 (33 kDa, Protein from Human poliovirus 3)
- 3-{3,5-dimethyl-4-[3-(3-methyl-isoxazol-5-yl)-propoxy]-phenyl}-5-trifluoromethyl-[1,2,4]oxadiazole (381 Da, Ligand)
- Capsid protein, vp0 (37 kDa, Protein from Human poliovirus 3)
- Glutathione (307 Da, Ligand)
Poliovirus type 2 (strain MEF-1) virus-like particle in complex with capsid binder compound 17
Resolution: 1.88 Å
EM Method: Single-particle
Fitted PDBs: 8ayz
Q-score: 0.769
Bahar MW, Nasta V, Fox H, Sherry L, Grehan K, Porta C, Macadam AJ, Stonehouse NJ, Rowlands DJ, Fry EE, Stuart DI
Commun Biol (2022) 5 pp. 1293-1293 [ DOI: doi:10.1038/s42003-022-04252-5 Pubmed: 36434067 ]
- Capsid protein, vp0 (37 kDa, Protein from Human poliovirus 2)
- Water (18 Da, Ligand)
- Capsid protein, vp1 (33 kDa, Protein from Human poliovirus 2)
- 4-[[4-[1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]sulfonylamino]benzoic acid (422 Da, Ligand)
- Sphingosine (299 Da, Ligand)
- Human poliovirus 2 (5 MDa, Virus from Human poliovirus 2)
- Capsid protein, vp3 (26 kDa, Protein from Human poliovirus 2)
Poliovirus type 3 (strain Saukett) stabilised virus-like particle (PV3 SC8).
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8anw
Q-score: 0.62
Sherry L, Grehan K, Swanson JJ, Bahar MW, Porta C, Fry EE, Stuart DI, Rowlands DJ, Stonehouse NJ
Viruses (2022) 14 [ Pubmed: 36298714 DOI: doi:10.3390/v14102159 ]
- Capsid protein, vp3 (26 kDa, Protein from Human poliovirus 3)
- Human poliovirus 3 (5 MDa, Virus from Human poliovirus 3)
- Capsid protein, vp1 (33 kDa, Protein from Human poliovirus 3)
- Capsid protein, vp0 (37 kDa, Protein from Human poliovirus 3)
- Sphingosine (299 Da, Ligand)
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6z6w
Q-score: 0.552
Bahar MW, Porta C, Fox H, Macadam AJ, Fry EE, Stuart DI
NPJ Vaccines (2021) 6 pp. 5-5 [ DOI: doi:10.1038/s41541-020-00267-3 Pubmed: 33420068 ]
- Human poliovirus 3 (5 MDa, Virus from Human poliovirus 3)
- Capsid proteins, vp1 (33 kDa, Protein from Human poliovirus 3)
- Capsid proteins, vp0 (37 kDa, Protein from Human poliovirus 3)
- Sphingosine (299 Da, Ligand)
- Capsid proteins, vp3 (26 kDa, Protein from Human poliovirus 3)
Poliovirus type 3 (strain Saukett) stabilized virus-like particle
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 5o5b
Q-score: 0.507
Marsian J, Fox H, Bahar MW, Kotecha A, Fry EE, Stuart DI, Macadam AJ, Rowlands DJ, Lomonossoff GP
Nat Commun (2017) 8 pp. 245-245 [ DOI: doi:10.1038/s41467-017-00090-w Pubmed: 28811473 ]
- Capsid proteins, vp1 (33 kDa, Protein from Human poliovirus 3)
- Human poliovirus 3 (5 MDa, Virus from Human poliovirus 3)
- Capsid proteins, vp2 (30 kDa, Protein from Human poliovirus 3)
- Capsid proteins, vp4 (7 kDa, Protein from Human poliovirus 3)
- Capsid proteins, vp3 (26 kDa, Protein from Human poliovirus 3)
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 5o5p
Q-score: 0.44
Marsian J, Fox H, Bahar MW, Kotecha A, Fry EE, Stuart DI, Macadam AJ, Rowlands DJ, Lomonossoff GP
Nat Commun (2017) 8 pp. 245-245 [ DOI: doi:10.1038/s41467-017-00090-w Pubmed: 28811473 ]
- 1-[5-[4-(ethoxyiminomethyl)phenoxy]-3-methyl-pentyl]-3-pyridin-4-yl-imidazol-2-one (408 Da, Ligand)
- Capsid proteins, vp1 (33 kDa, Protein from Human poliovirus 3)
- Human poliovirus 3 (5 MDa, Virus from Human poliovirus 3)
- Capsid proteins, vp2 (30 kDa, Protein from Human poliovirus 3)
- Capsid proteins, vp4 (7 kDa, Protein from Human poliovirus 3)
- Capsid proteins, vp3 (26 kDa, Protein from Human poliovirus 3)